ObjectiveTo understand the prognosis of patients with continuous ambulatory peritoneal dialysis (CAPD) and analyze its risk factors. MethodsA retrospective analysis was performed on the clinical and peritoneal dialysis-related data of CAPD patients who were regularly followed up in the First Affiliated Hospital of Guangxi Medical University from January 2007 to January 2022. The univariate and multivariate Cox proportional hazard regression models were used to analyze the risk factors for CAPD patients′ death. ResultsAmong the 477 CAPD patients, 168 cases withdrew from peritoneal dialysis (64 cases died, 75 cases converted to hemodialysis, 29 cases converted to kidney transplantation), with a total mortality rate of 13.42% (64/477). The main causes of death included cardiovascular and cerebrovascular diseases (32 cases, 50.00%), hemorrhage of digestive tract (18 cases, 28.13%), and sepsis (5 cases, 7.81%). The results of multivariate Cox proportional hazard regression model analysis showed that advanced age, diabetes mellitus, hypoproteinemia, dyslipidemia and hyperuricemia were independent risk factors for all-cause mortality in CAPD patients (all P＜0.05). ConclusionCAPD patients have high rates of peritoneal dialysis withdrawal and mortality, and advanced age, diabetes mellitus, hypoproteinemia, dyslipidemia and hyperuricemia are independent risk factors for CAPD patients′ death.

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