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自拟通络活血方辅助治疗急性缺血性脑卒中偏瘫的效果以及对患者平衡功能及生活活动能力的影响▲
Effects of adjuvant treatment of self-designed tongluo huoxue decoction on hemiplegia after acute ischemic stroke and its influence on balance function and living activity ability of patients

内科 202217卷01期 页码:17-20

作者机构:鲁山县人民医院(1 神经内科,2 内分泌科),河南省鲁山县467300

基金信息:▲基金项目:河南省医学科技攻关计划联合共建项目(LHGJ20191387)

DOI:DOI:10.16121/j.cnki.cn45-1347/r.2022.01.05

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目的探讨自拟通络活血方辅助治疗急性缺血性脑卒中偏瘫的效果以及对患者平衡功能及生活活动能力的影响。方法选取2019年10月至2020年10月我院收治的急性缺血性脑卒中偏瘫患者96例,采用随机数字法分为观察组和对照组,每组48例。对照组患者给予急性缺血性脑卒中偏瘫常规治疗,观察组患者在对照组的基础上辅以自拟通络活血方治疗,疗程8周。比较两组患者的临床疗效;比较两组患者治疗前后中医症候积分、平衡功能以及生活活动能力。结果治疗8周,观察组患者的治疗总有效率(91.67%)显著高于对照组(77.08%),差异有统计学意义(P<0.05)。治疗前,两组患者的中医症候积分比较,差异无统计学意义(P>0.05);治疗8周后,两组患者的中医症候积分均显著降低,观察组患者的积分显著低于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者的Berg平衡量表(BBS)和Barthel指数(BI)评分比较,差异无统计学意义(P>0.05);治疗8周后,两组患者的BBS量表和BI评分均显著升高,观察组患者的评分显著高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者的相对脑血流量(rCBF)、相对脑血容量(rCBV)和相对平均通过时间(rMTT)比较,差异无统计学意义(P>0.05)。治疗8周后,两组患者的rCBF、rCBV均显著增大,观察组的水平显著高于对照组;两组患者的rMTT均显著缩短,观察组患者的rMTT显著短于对照组,差异有统计学意义(P<0.05)。结论自拟通络活血方辅助治疗能显著提高急性缺血性脑卒中偏瘫的临床治疗效果,改善患者的临床症状,促进患者平衡功能恢复,提高患者的生活活动能力。
ObjectiveTo investigate the effects of adjuvant treatment of self-designed tongluo huoxue decoction on hemiplegia after acute ischemic stroke and its influence on balance function and living activity ability of patients. MethodsA total of 96 acute ischemic stroke patients with hemiplegia admitted to our hospital from October 2019 to October 2020 were enrolled and randomly divided into observation group and control group, with 48 cases in each group. The control group was given conventional treatment of acute ischemic stroke hemiplegia, based on which the observation group was supplemented with self-designed tongluo huoxue decoction, for an 8-week treatment course. The clinical efficacy was compared between the two groups. The scores of traditional Chinese medicine syndromes, balance function and living activity ability before and after treatment were compared between the two groups. ResultsAfter 8 weeks of treatment, the total effective rate of the observation group was higher than that of the control group (91.67% vs. 77.08%), with a statistically significant difference (P<0.05). Before treatment, there were no statistically significant differences in the scores of traditional Chinese medicine syndromes between the two groups (P>0.05). After 8 weeks of treatment, the traditional Chinese medicine syndromes scores of the two groups decreased significantly, and the observation group yielded lower scores in comparison with the control group, with statistically significant differences (P<0.05). Before treatment, there were no statistically significant differences on berg balance scale (BBS) and barthel index (BI) between the two groups (P>0.05). After 8 weeks of treatment, the scores of BBS and BI in both groups increased significantly, and the observation group yielded higher scores in comparison with the control group, with statistically significant differences (P<0.05). Before treatment, there were no statistically significant differences in relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV) and relative mean transmit time (rMTT) between the two groups (P>0.05). After 8 weeks of treatment, rCBF and rCBV in both groups increased significantly, and the levels of observation group were significantly higher than those of the control group. The rMTT of the two groups shortened significantly, and the rMTT in the observation group was shorter significantly than that of the control group, with a statistically significant difference (P<0.05). ConclusionThe self-designed tongluo huoxue decoction can prominently improve the clinical efficacy of acute ischemic stroke hemiplegia, improve the clinical symptoms of patients, promote the recovery of balance function and improve the ability of living activitiy of patients.

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