ObjectiveTo observe the clinical effect of vitamin D drops assisted for treating patients with osteoporosis and its influences on bone metabolism levels. MethodsEighty-one patients with osteoporosis admitted to our hospital from July 2018 to July 2019 were selected, and they were divided into control group (40 cases) and observation group (41 cases) according to the random number method. The patients in the control group administrated calcium citrate, based on which the observation group administrated vitamin D drops for treatment. The clinical efficacy after 3 months of treatment, and the pre- and post-treatment levels of serum 25(OH)D3, blood phosphorus, procollagen type I carboxy-terminal propeptide (PICP) and bone-specific alkaline phosphatase (BALP) were compared between the two groups. ResultsThe total effective rate of the observation group (80.5%) was significantly higher than that of the control group (57.5%), and the clinical efficacy was superior to that of the control group, with statistically significant differences (P＜0.05). Before treatment, there were no statistically significant differences in serum 25(OH)D3 and blood phosphorus levels between the two groups (P＞0.05). After 3 months of treatment, the levels of serum 25(OH)D3 and blood phosphorus in the two groups significantly increased, and the levels in the observation group were significantly higher than those in the control group, with statistically significant differences (P＜0.05). Before treatment, there were no statistically significant differences in the levels of PICP and BALP between the two groups (P＞0.05). After 3 months of treatment, the levels of PICP and BALP in the two groups significantly increased, and the levels in the observation group were lower than those in the control group, with statistically significant differences (P＜0.05). ConclusionVitamin D drops assisted for treating patients with osteoporosis has a significant clinical efficacy, and it can effectively improve bone metabolism status in patients.

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