目的探索广西大化瑶族轻度认知功能障碍(MCI)患者发病的危险因素以及MCI与颈动脉狭窄的关系。方法选取2015年2月至2016年5月在广西河池市大化县人民医院门诊及住院部治疗的瑶族MCI患者52例作为MCI组再选取同期在该院健康体检者80例瑶族老年人为对照组,比较两组研究对象的性别、年龄、高血压、饮酒、吸烟等情况,检测比较两组对象颈动脉狭窄和颈动脉狭窄分级情况。结果MCI组患者性别、年龄、文化程度、痴呆家族史和健康对照组比较,差异无统计学意义 (P>0.05);MCI组患者高血压、过度饮酒和吸烟比例显著高于对照组(P<0.05)。MCI组患者颈动脉狭窄率以及颈动脉狭窄Ⅱ和Ⅲ级所占比例显著高于健康对照组,差异有统计学意义(P<0.01或0.05)。结论广西大化地区瑶族MCI患者的发病可能与高血压、过度饮酒和吸烟有关,颈动脉狭窄很可能也是老年瑶族MCI患者发病的重要危险因素。
ObjectiveTo explore the risk factors of Yao mild cognitive impairment(MCI) and the relationship between mild cognitive impairment and carotid stenosis. MethodsA total of 52 cases of Yao elderly patients with MCI admitted to the People′s Hospital of Dahua Yao Autonomous County from January 2013 to January 2015 were selected as the MCI group, and 80 cases of the elderly Yao who had health check-up in the hospital at the same period were selected as the control group, gender, age, rate of drinking, smoking and high blood pressure were compared between the two groups, and the rate and grade of carotid stenosis of the two groups were detected. ResultsNo statistical significance was found between two groups in gender, age, educational level, family history of dementia(P>0.05); the rates of drinking, smoking and high blood pressure in the MCI group were significantly higher than those in the control group (P<0.05), the rates of carotid stenosis, grade Ⅱ and Ⅲ of carotid stenosis in the MCI group were significantly higher than those in the control group (P<0.05). ConclusionsThere could be correlation between drinking, smoking , high blood pressure and MCI in Dahua Yao County of Guangxi, carotid stenosis is an important risk factor of Yao MCI.