内科

目的探讨体外受精-胚胎移植（IVF-ET）女性患者伴侣亲密关系、社交焦虑与抑郁的现状，并重点分析伴侣亲密关系对社交焦虑及抑郁的影响。方法采用便利抽样法，选取2022年7月至2023年3月在广西壮族自治区生殖医院接受IVF-ET助孕治疗的300例女性不孕症患者作为研究对象。采用中文版Locke-Wollance婚姻调适量表（LWMAT）、中文版交往焦虑量表（IAS）和抑郁自评量表（SDS），分别评估患者的伴侣亲密关系、社交焦虑和抑郁状况。比较不同伴侣亲密关系状况患者的中文版IAS及SDS总分，并采用Pearson相关性分析探讨各研究变量间的相关性。结果 300例IVF-ET女性患者的中文版LWMAT总分为（106.60±12.37）分，其中伴侣亲密关系良好者213例（71.00%，伴侣亲密关系良好组）、伴侣亲密关系失调者87例（29.00%，伴侣亲密关系失调组）；中文版IAS总分为（48.90±9.54）分，其中低社交焦虑15例（5.00%）、中等社交焦虑132例（44.00%）、高社交焦虑153例（51.00%）；SDS总分为（56.35±8.31）分，其中无抑郁96例（32.00%）、轻度抑郁137例（45.67%）、中重度抑郁67例（22.33%）。伴侣亲密关系失调组的中文版IAS及SDS总分均高于伴侣亲密关系良好组（均P<0.05）。Pearson相关性分析结果显示，中文版LWMAT总分与中文版IAS总分、SDS总分均呈负相关（r分别为-0.658、-0.848，均P<0.05），中文版IAS总分与SDS总分呈正相关（r=0.544，P<0.05）。结论 IVF-ET女性患者伴侣亲密关系总体处于中等偏上水平，但仍有近三成患者存在伴侣亲密关系失调；超半数患者表现为高社交焦虑，近七成患者存在抑郁症状。伴侣亲密关系是影响IVF-ET女性患者社交焦虑与抑郁状况的重要因素。医护人员应重视对该人群伴侣亲密关系的评估，并通过以改善伴侣亲密关系为核心的夫妻共同干预策略，来缓解患者的焦虑、抑郁情绪，为优化IVF-ET治疗结局提供支持。

Objective To explore the current status of partner intimacy, social anxiety, and depression in women undergoing in vitro fertilization-embryo transfer (IVF-ET), and to focus on analyzing the impact of partner intimacy on social anxiety and depression. Methods A total of 300 women with infertility who received IVF-ET assisted reproductive technology at the Reproduction Hospital of Guangxi Zhuang Autonomous Region from July 2022 to March 2023 were selected as research subjects using the convenience sampling method. The Chinese version of Locke-Wollance Marital Adjustment Test (LWMAT), Chinese version of Interaction Anxiety Scale (IAS), and Self-rating Depression Scale (SDS) were used to assess the patients' partner intimacy, social anxiety, and depression, respectively. The total scores of Chinese version of IAS and SDS were compared among patients with different partner intimacy statuses, and Pearson correlation analysis was used to explore the intercorrelation of the study variables. Results The total score of the Chinese version of LWMAT for the 300 women undergoing IVF-ET was (106.60 ± 12.37) points. Among them, 213 women (71.00%) had a good partner intimacy (good partner intimacy group), while 87 women (29.00%) had a dysfunctional one (dysfunctional partner intimacy group). The total score of the Chinese version of the IAS was (48.90 ± 9.54) points. Specifically, 15 women (5.00%) had low social anxiety, 132 women (44.00%) had moderate social anxiety, and 153 women (51.00%) had high social anxiety. The total score of SDS was (56.35 ± 8.31) points. Of the participants, 96 women (32.00%) showed no depression, 137 women (45.67%) had mild depression, and 67 women (22.33%) had moderate to severe depression. The dysfuntional partner intimacy group had higher total scores on the Chinese version of the IAS and SDS than the good partner intimacy group (all P<0.05). Results of Pearson correlation analysis showed that the total score of Chinese version of LWMAT was negatively correlated with the total scores of Chinese version of IAS and SDS (r=-0.658, -0.848, respectively; all P<0.05), and the total score of Chinese version IAS was positively correlated with the total score of SDS (r=0.544, P<0.05). Conclusion The overall level of partner intimacy among women undergoing IVF-ET is moderately high. However, nearly 30% of patients still experience dysfuntional partner intimacy. More than half of the patients exhibit high social anxiety, and nearly 70% show depressive symptoms. Partner intimacy is a significant factor influencing social anxiety and depression in this population. Healthcare professionals should prioritize the assessment of partner intimacy and implement couple-based intervention strategies focused on improving intimacy to alleviate patients' anxiety and depression, thereby supporting optimized IVF-ET treatment outcomes.

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