Objective To investigate the influencing factors for lower limb deep venous thrombosis (DVT) in acute stroke patients complicated with severe paralysis. Methods The clinical data of 110 patients with first-episode acute stroke complicated with severe paralysis were retrospectively analyzed, and the patients were divided into a DVT group (n=19) or a non-DVT group (n=91) according to whether the lower limb DVT had occurred. A multivariate logistic regression model was used to analyze the risk factors for lower limb DVT in acute stroke patients complicated with severe paralysis. Results The results of the univariate analysis showed that there were statistically significant differences in terms of age, smoking history, atrial fibrillation history, thrombosis history, state of consciousness, bed rest ≥72 h or not, using dehydration drugs or not, and indwelling central venous catheter or not between the two groups (all P<0.05). The results of multivariate logistic regression analysis showed that age > 60 years, smoking, with the state of consciousness being in a coma, bed rest ≥ 72 h, and using dehydration drugs were risk factors for lower limb DVT in acute stroke patients complicated with severe paralysis (all P<0.05). Conclusion Age > 60 years, smoking, coma, bed rest ≥ 72 h, and using dehydration drugs are risk factors for lower limb DVT in acute stroke patients complicated with severe paralysis. Screening in such patients should be strengthened and targeted preventive measures should be taken in the clinical practice to reduce the occurrence risk of DVT.

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