内科

目的探讨老年住院患者营养状况、抑郁与生命质量的相关性，以及营养状况在抑郁与生命质量间的中介作用。方法采用便利抽样法选取2021年7月至2023年3月于南宁市某三级甲等医院老年病学科接受治疗的143例老年住院患者作为研究对象。采用一般资料调查表收集患者的一般资料，采用微型营养评定（MNA）、老年人抑郁量表（GDS）和欧洲五维健康量表中的视觉模拟量表（EQ VAS）分别评估患者的营养状况、抑郁状态和生命质量。采用Pearson相关性分析法探究老年住院患者营养状况、抑郁与生命质量的相关性，并采用温忠麟等提出的中介效应（Bootstrap法）检验方法检验营养状况在老年住院患者抑郁与生命质量间的中介效应。结果 143例老年住院患者MNA得分为（22.35±4.34）分，GDS得分为（3.14±4.29）分，EQ VAS得分为（91.52±9.76）分。MNA得分与GDS得分呈负相关（r=-0.408，P<0.001），与EQ VAS得分呈正相关（r=0.465，P<0.001）；GDS得分与EQ VAS得分呈负相关（r=-0.417，P<0.001）。营养状况在抑郁与生命质量间存在部分中介效应，中介效应占总效应的34.49%。结论老年住院患者的营养状况在其抑郁与生命质量间起部分中介作用，改善营养状况可以间接提升生命质量。

Objective To explore the correlations between the nutritional status, depression, and quality of life in elderly inpatients, as well as the mediation effect of the nutritional status between depression and quality of life. Methods By the convenience sampling method, 143 elderly inpatients who received treatment in the Geriatrics Department of a Class A tertiary hospital in Nanning from July 2021 to March 2023 were selected as the research subjects. The general information of the patients was collected by a general information questionnaire. The Mini Nutritional Assessment (MNA), the Geriatric Depression Scale (GDS), and the EuroQol Visual Analogue Scale (EQ VAS) were used to evaluate the patients' nutritional status, depressive state, and quality of life, respectively. The Pearson correlation analysis was used to explore the correlations between the nutritional status, depression, and quality of life in elderly inpatients. The mediation effect test method (Bootstrap method) proposed by Wen Zhonglin and others was adopted to analyse the mediation effect of the nutritional status between the depression and the quality of life in elderly inpatients. Results The MNA score of the 143 elderly inpatients was (22.35±4.34) points, the GDS score was (3.14±4.29) points, and the EQ VAS score was (91.52±9.76) points. The MNA score was negatively correlated with the GDS score (r=-0.408, P<0.001) and positively correlated with the EQ VAS score (r=0.465, P<0.001); the GDS score was negatively correlated with the EQ VAS score (r=-0.417, P<0.001). Nutritional status partially mediated the correlation between depression and quality of life, with a proportion of mediation up to 34.49%. Conclusion The nutritional status plays a partial mediating role between depression and quality of life in elderly inpatients, and improving the nutritional status can indirectly enhance their quality of life.

ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref
ref