内科

目的探讨二氢槲皮素联合保妇康栓治疗宫颈人乳头瘤病毒（HPV）感染的效果。方法选取66例宫颈HPV感染患者作为研究对象，随机将其分为传统治疗组和联合治疗组，每组33例。传统治疗组接受保妇康栓治疗，联合治疗组接受二氢槲皮素联合保妇康栓治疗，两组均持续治疗3个月。比较两组治疗前后的HPV-DNA载量、HPV转阴率和宫颈液基细胞学检查结果。结果治疗前，两组HPV-DNA载量差异无统计学意义（P>0.05）。治疗3个月后，联合治疗组HPV-DNA载量低于传统治疗组（P<0.05），HPV转阴率高于传统治疗组（P<0.05），宫颈液基细胞学检查结果优于传统治疗组。结论二氢槲皮素联合保妇康栓治疗宫颈HPV感染患者，可降低患者HPV-DNA载量，提高HPV转阴率，改善宫颈液基细胞学检查结果。

Objective To explore the effect of dihydroquercetin combined with Baofukang suppository in the treatment of cervical human papillomavirus (HPV) infection. Methods A total of 66 patients with cervical HPV infection were selected as the research subjects and randomly divided into a traditional treatment group or a combined treatment group, with 33 cases in each group. The traditional treatment group was treated with Baofukang suppository, the combined treatment group was treated with the combination of dihydroquercetin and Baofukang suppository, and both groups were treated continuously for 3 months. The HPV-DNA load, HPV negative conversion rate, and results of cervical liquid-based cytologic test were compared between the two groups before and after treatment. Results Before treatment, there was no statistically significant difference in the HPV-DNA load between the two groups (P>0.05). After 3 months of treatment, the HPV-DNA load in the combined treatment group was lower than that in the traditional treatment group (P<0.05), the HPV negative conversion rate was higher than that in the traditional treatment group (P<0.05), and the results of cervical liquid-based cytologic test were better than those in the traditional treatment group. Conclusion In the treatment of patients with cervical HPV infection, dihydroquercetin combined with Baofukang suppository can reduce the HPV-DNA load, increase the HPV negative conversion rate, and improve the results of cervical liquid-based cytologic test.

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