Objective To investigate the effects of Qingkailing injection on neurological function and inflammatory factor levels in patients with intracerebral hemorrhage (ICH). Methods A total of 86 patients with ICH were included and divided into a control group (43 cases, conventional treatment) or an observation group (43 cases, conventional treatment + Qingkailing injection) using the random number table method, and both groups were treated continuously for 2 weeks. The neurological function (National Institutes of Health Stroke Scale [NIHSS] score and modified Edinburgh Scandinavia Stroke Scale [MESSS] score) and levels of inflammatory factors (serum hypersensitive C-reactive protein [hs-CRP], interleukin [IL]-1β, IL-6, tumor necrosis factor-α [TNF-α]) before and after treatment, as well as the occurrence of adverse reactions during treatment, were compared between the two groups. Results After 2 weeks of treatment, NIHSS and MESSS scores and serum hs-CRP, IL-1β, IL-6, and TNF-α levels decreased in the two groups, and the decreases were more significant in the observation group (all P<0.05); there was no statistically significant difference in the adverse reaction between the two groups (P>0.05). Conclusion Qingkailing injection can improve neurological function and reduce levels of inflammatory factors when treating patients with ICH, with high safety.

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