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专栏:民族医药研究 | 更新时间:2026-02-03
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伸山拔石汤联合西药治疗湿热蕴结型急性痛风性关节炎疗效观察▲
Efficacy observation of Shenshan Bashi Decoction combined with Western medicine in treating acute gouty arthritis of dampness-heat accumulation type

内科 页码:665-670

作者机构:甘肃省武威肿瘤医院中西医结合科,武威市 733000

基金信息:甘肃省武威市科技计划B类项目(WW23B02SF033,WW24B01SF030) 通信作者:李应宏

DOI:10.16121/j.cnki.cn45-1347/r.2025.06.10

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目的 观察伸山拔石汤联合西药治疗湿热蕴结型急性痛风性关节炎(AGA)的临床疗效。方法 将90例湿热蕴结型AGA患者随机分为观察组和对照组,每组45例。对照组采用西药治疗(非布司他片+塞来昔布胶囊),观察组在对照组治疗的基础上联合应用伸山拔石汤治疗。两组均连续治疗14 d。比较两组治疗前后的中医证候积分、实验室指标(红细胞沉降率、C反应蛋白、血尿酸)、关节疼痛程度[视觉模拟量表(VAS)评分]、关节功能[Oswestry功能障碍指数(ODI)]、痛风累计发作次数,以及临床疗效。结果 治疗14 d后,观察组总有效率高于对照组(97.78%比80.00%,P<0.05);与对照组相比,观察组红细胞沉降率,C反应蛋白水平,血尿酸水平,关节疼痛、关节肿胀、屈伸不利积分和中医证候总积分,VAS评分,ODI,痛风累计发作次数均更低(均P<0.05)。结论 伸山拔石汤联合西药治疗湿热蕴结型AGA疗效显著,可缓解炎症反应,改善中医症候。

Objective To observe the clinical efficacy of Shenshan Bashi Decoction combined with Western medicine in treating acute gouty arthritis (AGA) of dampness-heat accumulation type. Methods Ninety patients with AGA of dampness-heat accumulation type were randomly divided into an observation group or a control group, with 45 patients in each group. The control group received Western medicine treatment (Febuxostat tablets + Celecoxib capsules), based on which the observation group received Shenshan Bashi Decoction additionally. Both groups were treated continuously for 14 days. Traditional Chinese medicine (TCM) syndrome scores, laboratory indicators (erythrocyte sedimentation rate, C-reactive protein, and serum uric acid), joint pain level (visual analogue scale [VAS] score), joint function (Oswestry Disability Index [ODI]), and cumulative number of gout attacks before and after treatment, as well as clinical efficacy, were compared between the two groups. Results After 14 days of treatment, the total effective rate in the observation group was higher than that in the control group (97.78% vs. 80.00%, P<0.05); compared with the control group, the observation group had lower levels of erythrocyte sedimentation rate, C-reactive protein, and serum uric acid, as well as lower scores for joint pain, joint swelling, restricted flexion and extension, total TCM syndrome score, VAS score, ODI, and a lower cumulative number of gout attacks (all P<0.05). Conclusion Shenshan Bashi Decoction combined with Western medicine is significantly effective in treating AGA of dampness-heat accumulation type, alleviating inflammatory response, and improving TCM symptoms.


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